Changelog

Current package versions and latest changes

This page summarizes the latest public package versions and short release notes for the core SigProfilerSuite tools. Detailed changelogs and release discussions remain in the corresponding GitHub repositories.

ToolCurrent PyPI versionLatest change summaryLinks
SigProfilerMatrixGenerator
Matrix generation
v1.3.6
Oct 28, 2025
Latest public PyPI release. Recent v1.3.x notes include documentation updates, custom output directory support, and maintenance of matrix-generation workflows. Releases
Changelog
Issues
SigProfilerPlotting
Visualization
v1.4.3
Jan 22, 2026
CI/GHCR deployment updates and compatibility fixes affecting tmbplot.py. Releases
Changelog
Issues
SigProfilerExtractor
De novo signature extraction
v1.2.6
Jan 6, 2026
Updated the default COSMIC reference version to v3.5 and updated the SigProfilerAssignment dependency for COSMIC v3.5 support. Releases
Changelog
Issues
SigProfilerAssignment
Signature decomposition and assignment
v1.1.3
Jan 24, 2026
Recent v1.1.x releases add COSMIC v3.5 support as the default reference and update reference files across supported genomes. Releases
Changelog
Issues
SigProfilerSimulator
Simulation and null models
v1.2.2
May 27, 2025
Added support for deterministic simulations using a seed file. Releases
Changelog
Issues
SigProfilerClusters
Clustered mutations
v1.2.2
Jul 23, 2025
Updates to the variant_caller parameter and plotting improvements. Releases
Changelog
Issues
SigProfilerTopography
Genomic topography
v1.0.108
Jan 2, 2026
Latest public package release for topography analyses of substitutions, dinucleotides, and indels across genomic features. Releases
Changelog
Issues

Version information reflects public PyPI releases and available GitHub changelog/release notes at the time this page was generated. For reproducible analyses, cite the specific package versions used in each project.